Azelastine embonate and compositions which contain it

Details Azelastine embonate and compositions which contain it Azelastine embonate and compositions which contain it

1990-10-15

1993-08-03

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514826, 540599, A61K 3155, C07D41300

Patent

active

052329194

ABSTRACT:
An embonic acid salt of azelastine is disclosed which does not possess the bitter taste of azelastine, and which therefore is suitable for orally administered formulations.

REFERENCES:
patent: 2925417 (1960-02-01), Elslager et al.
patent: 3813384 (1974-05-01), Vogelsang et al.
patent: 4704387 (1987-11-01), Engel et al.
J. Allergy Clin. Immunol. (Nov. 1988) p. 801, Multicenter, Double Blind, . . . , Efficacy & Safety Trial of Azelastine, Chlorpheniramine & Placebo . . . Weiler M. D.
M. Negwer: Org.-Chem. Drugs and Their Synonyms, vol. III, No. 6496, 1987, p. 1145.
German Search Report re: P 37 38 681.6.

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