Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1994-08-18
1996-04-23
Higel, Floyd D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514294, 540581, 546 94, A61K 31395, C07D45100, C07D45102, C07D45114
Patent
active
RE0352187
ABSTRACT:
An azatetracycle compound useful as 5HT.sub.3 antagonists of the general formula ##STR1## wherein D is a tetracycle of the structure ##STR2## wherein Ar is an aromatic moiety and B is either NH or O.
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Fludzinski et al, "Imidazoles As Indole Bioisosteres", J. Med. Chem., vol. 30, No. 9, pp. 1535-1537 (1987).
Becker Daniel P.
Flynn Daniel L.
Nosal Roger
Spangler Dale P.
Zabrowski Daniel L.
G. D. Searle & Co.
Higel Floyd D.
Kovacevic Cynthia S.
Williams Roger A.
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