Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-12-20
2011-10-11
Desai, Rita (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C514S278000
Reexamination Certificate
active
08034937
ABSTRACT:
The present invention is concerned with novel indol-3-yl-carbonyl-azaspiropiperidine derivatives as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use for the treatment of anxiety and depressive disorders and other diseases. In particular, the present invention is concerned with compounds of the general formula (I)wherein R1to R6, U, V, W, X, Y and Z are as defined in the specification.
REFERENCES:
patent: 2001/0039286 (2001-11-01), Dinnell et al.
patent: 2002/0052371 (2002-05-01), Fukami et al.
Dorwald F. A. Side Reactions in Organic Synthesis, 2005, Wiley: VCH, Weinheim p. IX of Preface.
Ebner et al., (2002), Eur. J. Neurosci. vol. 15 pp. 384-388.
Bielsky et al., (2004), Neuropsychopharmacology, vol. 29 pp. 483-493.
Liebsch et al., (1995), Regulatory Peptides vol. 59 pp. 229-239.
Michelini et al., (1999), Annals NY Acad. Sci. vol. 897 pp. 198-211.
Van Kerckhoven et al., (2002) Eur. J. Pharmacol. vol. 449 pp. 135-141.
Delgado et al., J. Org. Chem., vol. 10, p. 2862-2866 (1993).
Bissantz Caterina
Grundschober Christophe
Masciadri Raffaello
Ratni Hasane
Rogers-Evans Mark
Desai Rita
Hoffmann-La Roche Inc.
Johnston George W.
Prior Kimberly J.
Rocha-Tramaloni Patricia S.
LandOfFree
Azaspiro derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Azaspiro derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Azaspiro derivatives will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4273312