Azapurinones

Details Azapurinones Azapurinones

1975-05-06

1977-10-04

Drezin, Norman A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

2602565R, 424 45, 4242485, 424251, 424253, 42424852, C07D48704, A61K 31505

Patent

active

040523900

ABSTRACT:
8-Azapurin-6-ones substituted in the 2-position by a phenyl group carrying in a meta-position a sulphamoyl substituent, and also a hydroxy, alkoxy or alkylthio substituent para with respect to the said sulphamoyl grouping, and pharmaceutically acceptable salts thereof, possess pharmacological properties useful in the treatment of allergic respiratory disorders, for example allergic bronchial asthma.

REFERENCES:
patent: 3819631 (1974-06-01), Broughton et al.
patent: 3864493 (1975-02-01), Cairns et al.
patent: 3879544 (1975-04-01), Reisner et al.
patent: 3883653 (1975-05-01), Barth
patent: 3885038 (1975-05-01), Pfister et al.
Physicians' Desk Reference (PDR), (1974), p. 760.

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