Azadecalin amides and thioamides as inhibitors of cholesterol bi

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546146, A61K 3147, C07D21704

Patent

active

052781712

ABSTRACT:
The present invention provides certain novel azadecalin amides and thioamides which are useful as inhibitors of cholesterol biosynthesis and as agents which lower total serum cholesterol in patients in need thereof.

REFERENCES:
patent: 5039801 (1991-08-01), Brossi et al.
patent: 5124337 (1992-06-01), Dugan et al.

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