Azacycloalkane-2,2-diphosphonic acids

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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252136, 252180, 424199, 424200, 424 54, 260270K, 260239EP, 26029351, 26032661, 106111, 106313, 106315, C07F 938

Patent

active

039417727

ABSTRACT:
Azacycloalkane-2,2-diphosphonic acids having the formula ##EQU1## wherein R is a member selected from the group consisting of hydrogen and alkyl having from 1 to 3 carbon atoms and n is an integer from 3 to 5; as well as their water-soluble salts. The azacycloalkane-2,2-diphosphonic acids are excellent sequestering agents especially for alkaline earth metal ions. They are stabilizers for percompounds and are useful in the delaying of the setting times for gypsum.
In addition, the compound are useful in cosmetic preparations such as toothpastes and mouthwashes where they prevent formation of tartar and plaque and are useful in therapy in the treatment of diseases related to the abnormal deposition or dissolution of difficulty soluble calcium salts in the animal body.

REFERENCES:
patent: 3846420 (1974-11-01), Wollman

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