Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1975-10-02
1976-10-26
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
A61K 31675
Patent
active
039884430
ABSTRACT:
Azacycloalkane-2,2-diphosphonic acids having the formula ##EQU1## wherein R is a member selected from the group consisting of hydrogen and alkyl having from 1 to 3 carbon atoms and n is an integer from 3 to 5; as well as their water-soluble salts. The azacycloalkane-2,2-diphosphonic acids are excellent sequestering agents especially for alkaline earth metal ions. They are stabilizers for percompounds and are useful in the delaying of the setting times for gypsum.
In addition, the compound are useful in cosmetic preparations such as toothpastes and mouthwashes where they prevent formation of tartar and plaque and are useful in therapy in the treatment of diseases related to the abnormal deposition or dissolution of difficultly soluble calcium salts in the animal body.
Gloxhuber Christian
Ploger Walter
Schmidt-Dunker Manfred
Friedman Stanley J.
Henkel & Cie G.m.b.H.
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