Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1992-05-01
1994-05-31
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514 80, 514 89, 514102, 514107, 514824, A61K 31675, A61K 3166
Patent
active
053170156
ABSTRACT:
This invention relates to a method of lowering abnormally high serum cholesterol levels in the body without significantly reducing mevalonic metabolite synthesis and to novel pharmacological compositions containing as an active ingredient bisphosphonic acid and ester compounds containing a mono-, bi- or tricyclic ring linked with a bisphosphonate moiety through a basic amino alkylene group. This invention also provides novel bisphosphonate compounds and the processes for their preparation.
REFERENCES:
patent: 4416877 (1983-11-01), Bentzen et al.
patent: 5130304 (1992-07-01), Binderup et al.
patent: 5157027 (1992-10-01), Biller et al.
Burns Christopher J.
Cheney Daniel L.
Ullrich John W.
Youssefyeh Raymond D.
Jordan Kimberly R.
Nicholson James A.
Parker III Raymond S.
Rhone-Poulenc Rorer Pharmaceuticals Inc.
Savitzky Martin F.
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