Azabicyclooctane-carboxylic acids and pharmaceutical composition

Details Azabicyclooctane-carboxylic acids and pharmaceutical composition Azabicyclooctane-carboxylic acids and pharmaceutical composition

1981-10-20

1983-08-09

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424267, 546 84, 546112, A61K 3144, C07D22122

Patent

active

043978576

ABSTRACT:
Compounds of the formula ##STR1## in which A represents a vinylene or dimethylene radical, q is 0 or 1, R is an alkyl radical which can carry an amino group, X represents --S-- or --NH--, and R.sub.1 is a hydrogen atom or a radical of formula ##STR2## in which R.sub.2 is a hydroxy or alkoxy and R.sub.3 is a hydrogen atom or an alkyl, cycloalkylalkyl or phenylalkyl radical each having no more than a total of 8 carbon atoms, or an unsubstituted or substituted alkylthioalkyl radical.
These compounds are useful as medicaments, especially anti-hypertensive medicaments.

REFERENCES:
patent: 3833562 (1974-09-01), Fonken et al.
Albrecht, R., et al., Chem. Ber. 98, 1431-1434 (1965).

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