Azabicycloheptanes and process for their preparation

Details Azabicycloheptanes and process for their preparation Azabicycloheptanes and process for their preparation

1988-10-31

1989-11-28

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546183, C07D22122

Patent

active

048838772

ABSTRACT:
Compounds of the formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are, for example, H, alkyl, cycloalkyl, aryl or alkaryl are suitable as an ammonium salt-forming component for acid pharmaceutical active ingredients, and in particular for the preparation of azabicyclo[3.1.1.]heptane-substituted alkanediphosphonic acids for the treatment of diseases which can be attributed to disturbances in calcium metabolism.

REFERENCES:
patent: 4797406 (1989-01-01), Richardson et al.
patent: 4808718 (1989-02-01), Hartman et al.
Oppolzer et al., Ch. Abs. 84(3):17084n, 1976.
Alder, Helv. Ch. Act. 65(8), 1982, p. 2413.
Alder, J. Am. Ch. Soc. 105, p. 6712, 1983.

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