Azabicycloalkane oxime & azabicycloalkene oxime muscarinic agent

Details Azabicycloalkane oxime & azabicycloalkene oxime muscarinic agent Azabicycloalkane oxime & azabicycloalkene oxime muscarinic agent

1989-02-13

1990-06-26

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514214, 514305, 514413, 540477, 540582, 546133, 546137, 548453, A61K 3155, C07D45302, C07D48708

Patent

active

049372394

ABSTRACT:
Novel 1-azabicycloalkane- and alkene-oximes (Ia) and 8-azabicyclo[3.2.1]octane- and octene-oximes (Ib) are provided, these compounds being useful as agents for treating pain or for treating the symptoms of senile cognitive decline. Also provided are pharmaceutical compositions containing the compounds and methods of treatment using the compounds in dosage form. ##STR1##

REFERENCES:
Chemical Abstracts, 64:12642e(1966)[L. Mastafanova, et al., Khim. Geterotsikl. Soedin., Akad. Navk Latv. SSR 1965(6), 858-863].
Chemical Abstracts, 68:48774m (1968)[H. Fischer, et al., Helv. Chim. ACTA 51(1), 153-163 (1968)].
Chemical Abstracts, 90:38202p (1979)[K. Becker, et al., Helv. Chim. ACTA 1978, 61(7), 2596-2606].
Chemical Abstracts, 110:134964r (1989)[Evr. Pat. Appl. EP 264,091, T. Kamiya et al., 4/20/88.]
March, J. Advanced Organic Chemistry, McGraw Hill, New York, 1968, p. 675.

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