Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1994-02-01
1996-01-09
Lovering, Richard D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514305, 544116, 544119, 546133, 546137, A61K 31535, C07D45302, C07D41300
Patent
active
054829380
ABSTRACT:
Pharmaceutically useful nitrogen containing cyclic oxime and amine substituted compounds are disclosed which are azabicyclo[2.2.2]oximes, azabicyclo[2.2.2]-amines, azabicyclo[3.2.1]oximes and amine containing heterocyclic oximes wherein the heterocyclic ring contains from 3 to 7 carbon atoms.
REFERENCES:
patent: 4710508 (1987-12-01), Bergmeier et al.
The Lancet, v.2:1403, (1976), Davies et al., "Selective Loss of Central Cholinergic Neurons in Alzheimer's Disease".
Journal of Neurological Sciences, 34:247-265 (1977), Perry et al., "Neurotransmitter Enzyme Abnormalities in Senile Dementia".
The Lancet, v.1:668-670 (1977), White et al., "Neocortical Cholinergic Neurons in Elderly People".
Neurobiology of Aging, 4:25-30 (1983), Peterson et al., "Amelioration of Age-Related Neurochemical and Behavioral Deficits by 3,4-Diaminopyridin".
Experimental Aging Research, v.9, No. 3:211-214 (1983), Davis et al. "Improvement of 8-Arm Maze Performance in Aged Fischer 344 Rats . . .".
Brit. J. Psychiat., 138:46-50 (1981), Christie et al., "Physostigmine and Arecoline: Effects of Intravenous Infusions in Alzheimer Presenile Den".
Dissertation Abstract Int., B, 1984 45, (7), 2120; CA 102:113440 m.
Beilstein Abstract 6271688 of Stotter et al, Heterocycles 25, 1987, 259-262.
Lauffer David J.
Moos Walter H.
Pavia Michael R.
Tecle Haile
Thomas Anthony J.
Ashbrook Charles W.
Crissey Todd M.
Kilby Scalzo Catherine
Lovering Richard D.
Warner-Lambert & Company
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