Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1999-02-22
2000-09-19
Davis, Zinna Northington
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546112, A61K 3144, C07D22102
Patent
active
061212806
ABSTRACT:
This invention relates to novel azabicyclic compounds of the formula ##STR1## wherein R.sup.1, Q and Z are defined as in the specification, pharmaceutical compositions containing them, and the use of such compounds for the treatment of neurodegenerative diseases and other disorders involving nerve damage.
REFERENCES:
patent: 4405787 (1983-09-01), Gaitanopoulos et al.
Dennis A. Holt, et al., "Structure Activity Studies of Synthetic FKBP Ligands as Peptidyl-Prolyl Isomerase Inhibitors", Bioorganic and Medicinal Chemistry Letters, vol. 4, No. 2, pp. 315-320, (1994).
Maginni, et al. 'Imino Diels-Alder Cycloadditions: An Application to the Synthesis of (+/-)-Aristeromycin', vol.31, No. 43, Tetrahedron Letters 1990.
Blake James F.
Nagel Arthur A.
Davis Zinna Northington
Donahue E. Victor
Ginsburg Paul H.
Pfizer Inc.
Richardson Peter C.
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