Azabicyclic heterocycles as cannabinoid receptor modulators

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S236000

Reexamination Certificate

active

08030306

ABSTRACT:
The present application describes CB-1 inverse agonists according to Formula (I) and (Ia), pharmaceutical compositions comprising at least one compound according to Formula (I) or (Ia), and optionally one or more additional therapeutic agents and methods of treatment using the compounds according to Formula (I) or (Ia), both alone and in combination with one or more additional therapeutic agents. The preferred compounds have the general Formula (Ia), including all prodrugs, pharmaceutically acceptable salts and stereoisomer, thereof, wherein R1, R2, Ar1, Ar2are defined herein.

REFERENCES:
patent: 7629342 (2009-12-01), Ewing et al.
patent: 7777036 (2010-08-01), Kamboj et al.
patent: 2005/0171110 (2005-08-01), Yu et al.
patent: 2010/0216848 (2010-08-01), Peresypkin et al.
patent: WO 2005/063762 (2005-07-01), None
patent: WO 2005063762 (2005-07-01), None
patent: WO 2006/138682 (2006-12-01), None

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