Azabicyclic compounds, pharmaceutical compositions containing th

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

546 14, 546137, A61K 31435, C07D45300

Patent

active

052887308

ABSTRACT:
Compounds of formula (I), and salts and prodrugs thereof: ##STR1## wherein Q is the residue of an optionally substituted azabicyclic ring system;

REFERENCES:
patent: 3560510 (1971-02-01), Warawa
patent: 3833592 (1974-09-01), Papanastassiou
patent: 4599344 (1986-07-01), Morgan, Jr.
patent: 4843074 (1989-06-01), Rzeszotarski et al.
Otsuka, et al, "Role of Substance P As A Sensory Transmitter In Spinal Cord and Sympathetic Ganglia", 1982 Substance P in the Nervous System, CIBA Foundation Symposium 91, pp. 13-34.
Otsuka, TIPS, (Dec. 1987) vol. 8, pp. 506-510.
B. E. B. Sandberg, et al, J. Med. Chem. 1982, 25, No. 9 1009-1015.
Levine, et al Science, 1984 226, pp. 547-549.
Mantyh, et al, Neuroscience, 1988 25 (3) pp. 817-837.
D. Regoli, "Trends in Cluster Headache" Ed. Sicuteri, et al. Elsevier Scientific Publishers 1987 p. 85.
Kidd, et al, The Lancet, Nov. 11, 1989 "A Neurogenic Mechanism For Symmetrical Arthritis".
Gronblad, et al, "Neuropeptides In Synovium of Patients With Rheumatoid Arthritis & Osteoarthritis" J. Rheumatol 1988 15 (12) pp. 1807-1810.
O'Byrne, et al Arthritis & Rheumatism 1990, vol. 33, No. 7, pp. 1023-1028.
Kimball, et al, J. Immunol. 1988, 141 (10) pp. 3564-3569.
Mantyh, et al PNAS 1988, 85 pp. 3235-3239.
Yankner, et al Science, 1990 250 pp. 279-282.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Azabicyclic compounds, pharmaceutical compositions containing th does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Azabicyclic compounds, pharmaceutical compositions containing th, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Azabicyclic compounds, pharmaceutical compositions containing th will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-171451

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.