Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-09-25
1995-02-14
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546273, 544405, 544333, 5483121, C07D40112, C07D40312, A61K 3144
Patent
active
053896505
ABSTRACT:
Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.
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Frenette Richard
Gillard John W.
Hutchinson John H.
Prasit Petpiboon
Therien Michel
Merck Frosst Canada Inc.
Rose David L.
Rotman Alan L.
Yang Mollie M.
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