Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1990-09-28
1993-07-13
Springer, David B.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
548454, A61K 3140, C07D40112
Patent
active
052274888
ABSTRACT:
Indole derivatives of formula (I) ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 may be hydrogen or lower alkyl optionally substituted by halogen; X represents oxygen or sulfur; A.sup.1 represents a straight or branched alkylene chain containing from 2 to 4 carbon atoms; R.sup.5 is hydrogen or a straight or branched alkyl group; A.sup.2 is a straight or branched, saturated or unsaturated hydrocarbon chain containing from 2 to 6 carbon atoms; and R.sup.6 is selected from a group consisting of various structures, have been found to exhibit central nervous system activities.
REFERENCES:
patent: 3860609 (1975-01-01), Lundt
patent: 4216149 (1980-08-01), Asato
Zelesko et al., J. Med. Chem. (1983), 26 pp. 230-237.
Andersen Peter H.
Faarup Peter
Hansen John B.
Hansen Louis B.
Jeppesen Lone
Lambiris Elias J.
Novo Nordisk A S
Springer David B.
Zelson Steve T.
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