Aza-quinolinol phosphonate integrase inhibitor compounds

Details Aza-quinolinol phosphonate integrase inhibitor compounds Aza-quinolinol phosphonate integrase inhibitor compounds

2004-09-17

2008-12-09

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S009000, C546S123000

Reexamination Certificate

active

07462721

ABSTRACT:
Aza-quinolinol phosphonate compounds and methods for inhibition of HIV-integrase are disclosed.Ar is aryl or heteroaryl connecting R6to L. L is a bond or a linker connecting a ring atom of Ar to N. The ring atoms, X1-X5may be N, substituted nitrogen, or substituted carbon, and form rings. The compounds include at least one phosphonate group covalently attached at any site.

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