Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2002-07-29
2008-08-05
Seaman, D. Margaret (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C546S197000, C546S198000, C546S199000, C546S201000, C546S192000
Reexamination Certificate
active
07408067
ABSTRACT:
Compounds comprising an aza-cyclic portion and an aromatic portion linked via a sulphur atom are disclosed. The compounds disclosed are selective modulators of beta 4 subtype nicotinic acetylcholine receptors and are useful for the treatment of dysfunctions of the central and autonomic nervous systems.
REFERENCES:
patent: 4705853 (1987-11-01), Cale, Jr.
patent: 6124323 (2000-09-01), Bigge et al.
patent: 0 149 088 (1985-07-01), None
patent: 0 160 436 (1985-11-01), None
patent: 0 304 888 (1989-03-01), None
patent: 0 635 505 (1995-01-01), None
patent: WO 97/19059 (1997-05-01), None
patent: WO 99/32117 (1999-07-01), None
patent: WO 01/51469 (2001-07-01), None
patent: WO 01/81303 (2001-11-01), None
Radl, Arch Pharm Pharm med Chem, vol. 332, pp. 13-18, 1999.
Stanislav Radl et al.: Synthesis and Analgesic Activity of some Deaza Derivatives of Anpirtolin,Arch. Pharm. Pharm. Med. Chem., 1999, 13-18, 332.
Wang, Hao et al., Synthesis and biological activities of new 5-HT2A selective ligands N-substituted-piperidinyl-4-phenylthioether and sulfone derivatives,Yaoxue Xuebao, 2001, 274-277, vol. 36, 4.
Radl, Stanislav et al., Molecular Modification of Anpirtoline, a Non-Opioid Centrally Acting Analgesic,Collection of Czechoslovak Chem Comm, 1999, 363-376, vol. 64.
Astles Peter Charles
Baker Stephen Richard
Bonnefous Celine
Keenan Martine
Sanderson Adam Jan
Kronatin William
Merck & Co. , Inc.
Seaman D. Margaret
Todaro John C.
LandOfFree
Aza-cyclic compounds as modulators of acetylcholine receptors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Aza-cyclic compounds as modulators of acetylcholine receptors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aza-cyclic compounds as modulators of acetylcholine receptors will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4019330