Avian vaccine composition for the protection of poultry...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Combination of antigens from multiple bacterial species

Reexamination Certificate

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C424S234100, C424S257100, C424S243100, C424S252100, C424S258100, C435S243000, C435S173300

Reexamination Certificate

active

10837810

ABSTRACT:
There is provided a vaccine composition comprising a combination of a genetic deletion mutantS. typhimuriummicroorganism and a genetic deletion mutantE. colimicroorganism, suitable for mass application to poultry. Also provided is a safe and effective method to protect poultry against the ravages ofE. coliandSalmonellainfection and disease.

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patent: 6231871 (2001-05-01), Coloe
patent: 6902906 (2005-06-01), Chatfield
patent: 0 400 958 (1990-12-01), None
patent: 0 650 733 (1995-05-01), None
Gerard L. Cooper, et al., “Vaccination of chickens withSalmonella enteritidisaroA live oral salmonella vaccine,” Microbial Pathogenesis, 1990, vol. 9, pp. 255-265.
J.O. Hassan, et al., “Control of Colonization by VirulentSalmonella typhimuriumby Oral Immunization of chickens with Avirulent Δcya ΔcrpS. typhimurium,” Res. Microbiol., 1990, vol. 141, pp. 839-850.
Lei Wang, et al, “Immunization of mice wtth live oral vaccine based on aSalmonella enterica(sv Typhimurium) aroA strain expressing theEscherichia coli0111 0 antigen”/ Microbial Pathogenesis 1999; 27: 55-59.
“Safety, Immunogenicity, and Efficacy of TwoEscherichia colicyp crp Mutants as Vaccines for Broilers”. Avian Diseases 46:287-297, 2002.

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