Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant virus encoding one or more heterologous proteins...
Patent
1998-09-24
2000-11-14
Salimi, Ali
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant virus encoding one or more heterologous proteins...
4242041, 4242071, 4353201, 4352351, 530300, 530350, 536 2372, A61K 3912, A61K 3921, C12N 1500
Patent
active
061466417
ABSTRACT:
The envelope (env) gene from avian leukosis virus subgroup J (ALV-J) strain Hc1 has been isolated, sequenced and cloned into an expression vector. The ALV-J Hc1 env gene and expressed protein are useful for development of diagnostic assays to detect Hc1-specific nucleic acid and proteins and for eliciting an immune response in chickens.
REFERENCES:
Venugopal, K., et al., "Antigenic variants of J subgroup avian leukosis virus: sequence analysis reveals multiple changes in the env gene", Journal of General Virology, 2998, 79, pp. 757-766, 1998.
Venugopal, K., et al., "Recombinant env-gp85 of HRS-103 (Subgroup J) Avian Leukosis Virus:Antigenic Characteristics and Usefulness as a Diagnostic Reagent", Avian Diseases, 41, 1997, pp. 283-288.
Fadly, A. M., et al., "Some Characteristics of a Subgroup J-Like Avian Leukosis Virus Isolated from Broiler Breeder Chickens in the United States", Abstract, Aug. 18-22, 1997, Budapest Hungary, XIth International Congress of the World Veterinary Poultry Association.
Fadly, A.M., et al,, "An Overview of Subgroup J-Like Avian Leukosis Virus Infection in Broiler Breeder Flocks in the United States", Abstract, Avian Tumor Viruses Symposium, Jul. 24, 1997, 40th Annual Meeting, Reno, Nevada, American Association of Avian Pathologists.
Fadly, Aly M., "Elocytomatosis: An Emerging Disease of Broiler Breeder Chickens", Abstract, Proceedings of the Forty-Seventh Western Poultry Disease Conference, Mar. 8-10, 1998, Sacramento, CA.
Bai, J., et al., "Sequence of host-range determinants in the env of a full-length, infectious proviral clone of exogenous avian leukosis virus HPRS-103 confirms that it represents a new subgroup (designated J)", Journal of General Virology, 1995, 76, pp. 181-187.
Bai, J., et al., "HPRS-103 (Exogenous Avian Leukosis Virus, Subgroup J) Has an env Gene Related to Those of Endogenous Elements EAV-O and E51 and an E Element Found Previously Only in Sarcoma Viruses", Journal of Virology, Feb. 1995, vol. 69, No. 2, pp. 779-784.
Fadly Aly M.
Hunt Henry D.
Lee Lucy F.
Fado John D.
Ribando Curtis P.
Salimi Ali
Silverstein M. Howard
The United States of America as represented by the Secretary of
LandOfFree
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