Avian interleukin-2

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.

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530415, 530416, 530417, 530827, 530837, 435 701, 43524021, 43524022, 43524025, C07K 1500, C12N 506

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active

050345133

ABSTRACT:
A substantially pure species of avian Interleukin-2 has a molecular weight of about 30 kda. as determined by SDS-polyacrylamide gel electrophoresis. The compound is obtained from avian lymphocytes. It is produced by collecting lymphocytes from an avian donor, growing the lymphocytes in a medium containing a T cell mitogenic agent, and recovering the compound from the medium.

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Schat, K. A., Calnek, B. W., and Weinstock, D., "Cultivation and Characterization of Avian Lymphocytes with Natural Killer Cell Activity", Avian Pathology, 15, pp. 539-556 (1986).
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G. Kromer et al., "Avian Lymphokines: An Improved Method for Chicken IL-2 Production and Assay. A Con A-Erythrocyte Complex Induces Higher T-Cell Proliferation . . . ", J. Immunol. Methods 73: 273-281 (1984).
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D. Riendeau et al., "Purification of Mouse Interleukin-2 to Apparent Homogeneity", Communication in J. Biol. Chem. 258(20): 12114-12117 (1983).

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