Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1994-12-01
1996-08-27
Wityshyn, Michael G.
Chemistry: molecular biology and microbiology
Spore forming or isolating process
43524025, 4352351, 435 701, 435 703, 435 11, 4242041, 4242061, 4242311, C12N 500, C12N 502, C12N 700, C12P 2104, A01N 102, A61K 3912, A61K 39145, A61K 39245
Patent
active
055500510
ABSTRACT:
The invention relates to a biomass for producing virus/virus antigen, which consists of cell aggregates of avian embryo cells having diameters of between 100 .mu.m and 1,000 .mu.m. The biomass according to the invention has a high metabolic activity in suspension in the culture medium and is infected with virus. It enables the large-scale production of pure virus/virus antigen and is particularly suitable for the production of TBE-virus/virus antigen.
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patent: 4335215 (1992-06-01), Hu et al.
patent: 5114855 (1992-05-01), Hu et al.
patent: 5391491 (1995-02-01), Mundt et al.
Slavik et al., "Optimalized Conditions of Tick-borne Encephalitis Virus Production in vitro", Acta Virologica, vol. 27, Mar. 1983.
Samuel et al., Rev. Roum. Med.-Virol., 32 (2): 145-54 (1981).
Dorner Friedrich
Eibl Johann
Mundt Wolfgang
Woehrer Wilfried
Dadio Susan M.
Immuno Aktiengesellschaft
Wityshyn Michael G.
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