Avermectin formulation

Details Avermectin formulation Avermectin formulation

1996-01-29

1998-06-30

Peselev, Elli

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

A61K 3170

Patent

active

057734224

ABSTRACT:
Novel formulations are disclosed for the administration of an avermectin, based upon the use of N-methylpyrrolidone or 2-pyrrolidone or mixtures thereof to dissolve avermectin. Formulations can contain from 0.1 to 40% by weight dissolved in at least 5% by volume of N-methylpyrrolidone, 2-pyrrolidone or mixture thereof. Various formulations are suitable for administration by intramuscular or subcutaneous injection, by topical application, stomach intubation, oral and drench administration.

REFERENCES:
patent: 4772460 (1988-09-01), Malook et al.
patent: 4853372 (1989-08-01), Williams et al.
patent: 4912090 (1990-03-01), Yanai et al.
patent: 4916120 (1990-04-01), Roben et al.
Analytical Profiles of Drug Substances; vol. 17, pp. 156-184; "Ivermectin" by David W. Fink (1988).

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