Avermectin derivatives with a spacer inserted between the disacc

Details Avermectin derivatives with a spacer inserted between the disacc Avermectin derivatives with a spacer inserted between the disacc

1990-05-14

1992-05-19

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 71, A61K 3170, C07H 1704

Patent

active

051149303

ABSTRACT:
There are disclosed avermectin derivatives which incorporate a spacer between the disaccharide and the aglycone. The synthetic spacer-containing analogs are derived from the corresponding aglycones which in turn are prepared by chemical modification of naturally occurring avermectins. The compounds are active antiparasitic agents and compositions for that use are disclosed.

REFERENCES:
patent: 4587247 (1986-05-01), Linn et al.

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