Avermectin derivatives

Details Avermectin derivatives Avermectin derivatives

1993-02-24

1995-05-02

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 71, 549264, 514450, A61K 3170, C07H 1704

Patent

active

054119464

ABSTRACT:
Avermectin derivatives, wherein the C-17-21-25-dioxaspirane substructure has been modified to include substitutions of heteratomic nucleophilic thiols at the 23,24-.alpha.-epoxide. These compounds can be similarly substituted at the 4"-, 5-, 13, and 25-positions. The new C-23 and C-24 substituted avermectin derivatives are potent anthelmintic, insecticidal and acaricidal agents.

REFERENCES:
patent: 4310519 (1982-01-01), Albers-Schonberg et al.
patent: 4550160 (1985-10-01), Mrozik
patent: 4895837 (1990-01-01), Mrozik et al.
patent: 4897383 (1990-01-01), Sinclair
patent: 4906619 (1990-03-01), Eskola et al.
patent: 4945105 (1990-07-01), Sato et al.
patent: 5015630 (1991-05-01), Fisher et al.
patent: 5023241 (1991-06-01), Linn et al.
patent: 5089480 (1992-02-01), Gibson et al.

Affiliated with

Also associated with

Rating

Avermectin derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Avermectin derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Avermectin derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1137111