Avermectin derivatives

Details Avermectin derivatives Avermectin derivatives

1989-01-13

1990-01-23

Lilling, Herbert J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 71, 549264, 71 88, 514450, A61K 3170, C07H 1704, C07P31306

Patent

active

048958379

ABSTRACT:
There are disclosed novel avermectin .DELTA. 23,24-derivatives (also referred to as 23,24-dehydro compounds). The compounds are prepared by selective dehydration of avermectin A2 or B2 compounds. The avermectin compounds have utility as anti-parasitic agents and compositions for that use are also disclosed. The compounds are also highly potent insecticides against agricultural pests. The .DELTA. 23,24-avermectin compounds have increased activity relative to the A2 or B2 compounds.

REFERENCES:
patent: 4199569 (1980-04-01), Chabala et al.
patent: 4310519 (1982-01-01), Albers-Schonberg et al.
patent: 4550160 (1985-10-01), Mrozik

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