Imperforate bowl: centrifugal separators – With condition responsive means
Patent
1994-01-21
1995-08-01
Scherbel, David A.
Imperforate bowl: centrifugal separators
With condition responsive means
494 10, 604 6, B04B 910, A61M 136
Patent
active
054375983
ABSTRACT:
A plasma sequestration system having a volume control system is provided. When a calculated volume of whole blood has been processed, the system switches from a fill to an empty cycle. The termination point is calculated in advance, based on the desired composition of the collected plasma, thus improving process control and product uniformity. The system is automated or partially automated using an optical sensor or marker to monitor the volume of packed red blood cells. When the red cells reach the marker or sensor, a signal is sent to the control system which then calculates the required fill volume. Processing continues until the calculated fill volume is reached, at which time the system automatically stops the collection cycle. The system also provides for two speed operation of the centrifuge as a safeguard against foaming which may result in aerosol formation and blood trauma. Foaming is reduced by reducing centrifuge speed as the packed red blood cells approach the stationary deflector in the centrifuge bowl.
REFERENCES:
patent: 3655123 (1972-04-01), Judson
patent: 4146172 (1979-03-01), Cullis
patent: 4151844 (1979-05-01), Cullis et al.
patent: 4464167 (1984-08-01), Schoendorfer
patent: 4498983 (1985-02-01), Bilstad et al.
patent: 4608178 (1986-08-01), Johannson et al.
patent: 5102407 (1992-04-01), Carmen et al.
patent: 5154716 (1992-10-01), Bauman et al.
patent: 5199938 (1993-04-01), Kohlstette
patent: 5281342 (1994-01-01), Biesel et al.
patent: 5348533 (1994-09-01), Papillon et al.
T. Simon et al., "Storage and Transfusion of Platelets Collected by an Automated Two-Stage Apheresis Procedure", (1992) Transfusion 32:624-628.
C. F. Hogman, "The Bottom and Top System: A New Technique for Blood Component Preparation and Storage", (1988), Vox Sang 55:211-217.
R. G. Strauss et al., "Comparison of autosurge versus surge protocols for discontinuous-flow centrifugation plateletapheresis", (1987), Transfusion 27:6 pp. 499-501.
J. P. AuBuchon et al. "Optimization of Parameters for Maximization of Plateletpheresis and Lymphocytapheresis Yields on the Haemonetics Model V50", (1986), J. Clin. Apheresis 3:103-108.
Cobe Laboratories, Inc.
Scherbel David A.
Till Terrence R.
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