Automatic sequencer/genotyper having extended spectral response

Details Automatic sequencer/genotyper having extended spectral response Automatic sequencer/genotyper having extended spectral response

1996-08-22

1999-02-16

Beisner, William H.

Chemistry: electrical and wave energy

Processes and products

Electrophoresis or electro-osmosis processes and electrolyte...

204452, 204603, 204612, G01N 2726, G01N 27447

Patent

active

058716289

ABSTRACT:
An advanced imaging spectrograph system provides for slab-gel DNA sequencing and genotyping with high throughput sequencing. The system is based on the integration of improved electrophoresis structures with an imaging spectrophotometer that records the entire emission spectra along an imaging line across a sequencing gel (or capillary array). The system includes spectral shape matching to improve dye identification allowing the use of dyes having nearly any emission spectra and allowing greater than four dye multiplexing.

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