Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...
Reexamination Certificate
2003-03-24
2009-02-17
Lucchesi, Nicholas D. (Department: 3763)
Surgery
Means for introducing or removing material from body for...
Treating material introduced into or removed from body...
C604S504000, C700S028000
Reexamination Certificate
active
07491187
ABSTRACT:
Present invention is a system of blood glucose monitoring and intensive insulin therapy in a ICU for strict maintenance of normoglycemia which reduces intensive care and hospital mortality and morbidity of critically ill adult patients. The findings of present study also reveal factors determining insulin doses needed to maintain normoglycemia as well as the impact of insulin dose versus blood glucose level on the observed outcome benefits have been established. The invention provides a control system that adapts the flow of the insulin infusion based on insulin requirement calculated by blood glucose levels and clinical parameters such as history of diabetes, Body Mass Index, blood glucose level on admission, reason of ICU admission, time in the ICU, type and severity of illness, caloric intake, obesity, drugs affecting insulin sensitivity). This automated insulin monitoring systems significantly reduces the workload and human resource management problems for intensive insulin therapy in patients in the ICU.
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Communication from European Patent Office for European Patent Application No. EP 03 711 717.3 dated Sep. 18, 2008.
Aerts Jean-Marie
Berckmans Daniel
De Moor Bart
De Smet Frank
Pluymers Bert
Clark & Elbing LLP
K.U. Leuven Research & Development
Lucchesi Nicholas D.
Stigell Theodore J
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