Automatic cryoloop alignment for protein crystals

X-ray or gamma ray systems or devices – Accessory – Alignment

Reexamination Certificate

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C378S073000, C378S098500

Reexamination Certificate

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07438472

ABSTRACT:
Methods and apparatus for implementing robust and efficient cryoloop auto-centering for crystal location and alignment to the x-ray beam are provided. Image processing techniques are used for recognition of the small protein crystals. The detected crystal location enables crystal positioning in the x-ray beam, and optimization of the x-ray optics such as beam profile and intensity to the size and shape of the protein crystals.

REFERENCES:
patent: 6404849 (2002-06-01), Olson et al.
patent: 7274769 (2007-09-01), Nordmeyer et al.

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