Automated urinalysis method

Details Automated urinalysis method Automated urinalysis method

1995-04-24

1996-05-14

Alexander, Lyle A.

Chemistry: analytical and immunological testing

Optical result

436 17, 436 63, 436175, G01D 2175

Patent

active

055167004

ABSTRACT:
A method that provides techniques for determination of urinary constituents (Blood (Red Blood Cells/Hemoglobin), Leukocytes, pH, Specific Gravity, Bacterial Reductase/Nitrite/Indole activity, Total Ketone Bodies, Protein, and Glucose) at low chemically significant levels with a carrier independent reagent system that can be placed on a high throughput autoanalyzers. Thus, giving the analyst the ability to run multiple urinary assays on a single sample of urine simultaneously with the ability to compare to reference standards on the same run. This system is designed to neutralize urinary interfering substances. This method is fast, efficient, an adaptable to many of the currently available discrete and continuous flow automated analyzers, effective at sample to reagent ratios of 1 to 13 or more. This method is applicable to samples with high turbidity, high ionic strength, high color content, wide pH extremes, and buffer strengths, among other interfering substances.

REFERENCES:
patent: 3907503 (1975-09-01), Betts et al.
patent: 4755472 (1988-06-01), Ismail et al.
patent: 5128265 (1992-02-01), Meiattini

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