Agitating – By movement of support for removable mixing chamber
Patent
1996-08-02
1998-10-06
Soohoo, Tony G.
Agitating
By movement of support for removable mixing chamber
366140, 366142, 366213, 73 6171, 73866, 422270, 422277, G01N 138, B01F 100
Patent
active
058167013
ABSTRACT:
In a preferred embodiment, the apparatus includes a dissolution vessel removably seated within an aluminum platen. The apparatus also includes an assembly for automatically measuring a desired volume of media, heating and degassing the volume of media and then dispensing the volume of media into the dissolution vessel. In addition, the apparatus includes a carousel having a plurality of compartments, the carousel being rotatably mounted on a stage, the stage being alignable with the vessel. According to one mode of operation, an open-top, cage-type basket is placed in one or more compartments of the carousel, each basket containing a tablet intended for dissolution. The apparatus additionally includes a shaft aligned with the vessel, the bottom end of the shaft being adapted to frictionally fit together with a basket. The shaft is rotatable and vertically movable so that it can fit together with a basket, pick the basket up out of the carousel, lower the basket into the vessel, rotate the basket within the media and remove the basket from the media. The apparatus further includes a catheter automatically movable in and out of the vessel for sampling the media at desired times, an automated mechanism for loading and replacing a depth filter on the input end of the catheter, an automated mechanism for removing the basket from the end of the shaft after testing has been completed and an automated mechanism for removing media from the vessel after testing has been completed. The apparatus also includes a paddle shaft which may be used interchangeably with the basket shaft if tablets are placed directly in the compartments of the carousel and are then dispensed from the carousel into the vessel through an opening in the bottom of each carousel that is alignable with an opening in the stage.
REFERENCES:
patent: 2843169 (1958-07-01), Stein
patent: 3467500 (1969-09-01), Wilkinson et al.
patent: 3791222 (1974-02-01), Goodhart et al.
patent: 3802272 (1974-04-01), Bischoff et al.
patent: 4681858 (1987-07-01), Chaudhari et al.
patent: 4792434 (1988-12-01), Metzger et al.
patent: 4856909 (1989-08-01), Mehta et al.
patent: 4879917 (1989-11-01), Eppelmann et al.
patent: 4924716 (1990-05-01), Schneider
patent: 5076107 (1991-12-01), Timmermans et al.
patent: 5174508 (1992-12-01), Martin
patent: 5380485 (1995-01-01), Takhashi et al.
patent: 5403090 (1995-04-01), Hofer et al.
Article entitled, "A fully automated, benchtop dissolution testing workstation," by Richard Buechsenschuetz, published before the present patent application.
Sales literature for Zymark Corp.'s Multidose workstation, published before the present patent application.
Sales literature for Scientific Instruments and Technology Corp.'s PHARMA TEST dissolution baths, published before the present patent application.
Earle Richard S.
Kerr Warren P.
Martin Arthur L.
Martin James L.
McDowell Ronnie
Soohoo Tony G.
Source For Automation, Inc.
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