Automated system for performing fluorescent immunoassays

Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Sample mechanical transport means in or for automated...

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23230B, 23915, 422 67, 364497, G01N 3354

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active

042711231

ABSTRACT:
A sample analyzer for quantitating relatively small amounts of clinically significant compounds in a liquid sample together with a sample mixing device (sampler) is disclosed. The analyzer has a transparent cell for holding the liquid sample. A light source focuses a stable light beam onto the sample so that fluorescent particles in the sample cause fluorescent emissions, the intensity of which is a function of the intensity of the light beam and the concentration of fluorescent particles in the sample. A detector in optical communication with the cell receives and senses photons forming the fluorescent emissions of the particles when excited by the light beam. The sampler holds a multiplicity of vials in an upright position in a row, advances the vials in incremental steps to present them at an aspiration station and includes an aspirator having a downwardly open suction tube that is vertically inserted into and withdrawn from the vials. A vacuum source withdraws the liquid sample from the vials through the suction tube and flows it to the sample cell in the analyzer. A mixer surrounds the suction tube and is activated before the sample is withdrawn form a uniform suspension.

REFERENCES:
patent: 3728079 (1973-04-01), Moran
patent: 4043756 (1977-08-01), Sommervold
patent: 4150949 (1979-04-01), Smith
patent: 4153675 (1979-05-01), Kleinerman
patent: 4170625 (1979-10-01), Welch
patent: 4201763 (1980-05-01), Monthony et al.

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