Automated prolonged slow release intrauterine insemination using

Details Automated prolonged slow release intrauterine insemination using Automated prolonged slow release intrauterine insemination using

1995-03-07

1999-05-18

Buiz, Michael

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

604104, 606193, A61M31/00

Patent

active

059046651

ABSTRACT:
A method of automated prolonged slow release artificial intrauterine insemination is disclosed wherein motile sperm are introduced into the uterus in a programmed, organized and metered pattern over an extended period of time. A catheter is inserted into the uterine cavity and aliquots of sperm containing medium are injected at a rate of 10 to 20 mm/hr (approximately every 30 seconds) for between 4 to 6 hours. The motile sperm content of each aliquot is between 8,000 to 75,000. Preferably, the method is carried out with the use of a novel delivery device. The device of the present invention comprises a flexible catheter having a delivery channel, a first end attachable to a pumping means, and a second end (uterine end) adapted to pass through the cervix and into the uterine cavity. The catheter is provided with an inflatable balloon adjacent the second end. Upon inflation of the balloon, the catheter is immobilized in the vagina. The pumping means delivers the aliquots of sperm containing medium through the delivery channel and into the uterus. The pumping means is adapted to pump sufficient medium to deliver between 1 million to 9 million motile spermatozoa per hour into the uterine cavity. The balloon is deflatable to permit the catheter's easy removal after use. Preferably, the pumping means may be strapped to the abdomen of the patient to permit the patient to leave the treatment center during the treatment period.

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Muharib et al, "Slow Release Intrauterine Insemination Versus the Bolus Technique in the Treatment of Women with Cervical Mucus Hostility," Human Reproduction, vol. 7, No. 2, pp. 227-229, 1992.
Muharib and Gadir; Abstract from the X111 World Congress on Fertility and Sterility, Oct. 1989.

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