Automated process for preparing treated microparticles especiall

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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4352401, 435 2, 436174, 424 9373, 424533, G01N 3349

Patent

active

056817096

ABSTRACT:
A method for preparing treated naturally occurring or synthetic particles using a blood cell processor is provided. The method comprises adjusting the blood cell processor to allow a dispersion of such particles to come into contact with a treatment material in an amount and for a period of time sufficient to modify all or a portion of the surface of such particles. In a preferred embodiment, the method comprises washing collected red blood cells; separating a selected volume of said washed red blood cells; and treating one portion of said separated washed cells with a selected proteolytic enzyme, to prepare a red blood cell reagent.

REFERENCES:
patent: 3737096 (1973-06-01), Jones et al.
patent: 4107287 (1978-08-01), Morton et al.
patent: 4306556 (1981-12-01), Zelman
patent: 4804363 (1989-02-01), Valeri
patent: 4839058 (1989-06-01), Cawley et al.
Andersson, T.R. "Preparation of Antibody-Coated red cells by the Haemonetics Cell Separator or Cell Washer" 1979 Vox Sang, 36:312.

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