Automated Peptide design and synthesis

Details Automated Peptide design and synthesis Automated Peptide design and synthesis

1989-08-25

2000-02-29

Davenport, Avis M.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Synthesis of peptides

530333, A61K 3800, C07K 500, C07K 700

Patent

active

06031074&

ABSTRACT:
An automated peptide design and synthesis method is provided, wherein peptides are synthesized on interior, inward facing surfaces of reservoirs formed in a solvent resistant substrate. Novel substrates, as well as novel solutions for storing protected carboxyl terminal amino acids, are also provided.

REFERENCES:
patent: 3725380 (1973-04-01), Monig et al.
patent: 3944538 (1976-03-01), Bodanszky
patent: 3953415 (1976-04-01), Kisfaludy et al.
patent: 4192798 (1980-03-01), Verlander et al.
patent: 4330440 (1982-05-01), Ayers et al.
patent: 4436874 (1984-03-01), Asipsi et al.
patent: 4631211 (1986-12-01), Houghten
patent: 4812512 (1989-03-01), Buendia et al.
Geysen et al., PNAS USA vol. 81 pp. 3998-4002 (Jul. 1984).
Melby, Macromolecules, vol 11, No. 1 (Jan./Feb. 1978). pp. 50-56.
Proc. Natl. Acad. Sci. USA, vol. 82, pp. 5131-5135, Aug. 1985 Immunology, Richard A. Houghten.
Angewandte Chemie, International English Edition, vol.24,No.10, pp. 799-892, Oct. 1985.
Journal of American Chem.Soc., vol. 89, No. 1, pp.183-184, Jan. 1967.
Science, vol. 150, pp. 178-185, Oct. 1965.
Merrifield R.B. 24 Angen Chemie No. 10 (1985) pp. 799-810.
Daniels et al., 30 Tetrahedron Letters No. 33 pp. 4345-4348 (Sep. 6, 1989).
Beauchamp et al. 131 Analytical Biochem. 25-33 (1983).
Arshady et al. J. C. S . Perkins Tran I 529-537 (1981).
Melby CA 1218775 vol. 88 (1978).
Ryazanteev CA 72818 F vol. 78 (1973).
Stewart and Young, "Solid Phase Peptide Synthesis" (2nd ed) (Pierce Chemical Co 1984) 1-7.
Houghten, PNAS USA, vol. 82 pp. 5131-5135 (Aug. 1985).
Geysen et al, PNAS USA vol. 81 pp. 3998-4002 (Jul. 1984).
Ryzanteev et al CA 72818F vol. 78 (1973).
Melby Macromolecules vol. 11 No. 1 (Jan./Feb. 1978).

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