Chemistry: electrical and wave energy – Apparatus – Electrophoretic or electro-osmotic apparatus
Patent
1998-06-29
2000-02-22
Warden, Jill
Chemistry: electrical and wave energy
Apparatus
Electrophoretic or electro-osmotic apparatus
204451, 204452, 204453, 204455, 204601, 204604, 204605, 356344, G01N 2726, G01N 27477
Patent
active
060276274
ABSTRACT:
An automated electrophoretic system is disclosed. The system employs a capillary cartridge having a plurality of capillary tubes. The cartridge has a first array of capillary ends projecting from one side of a plate. The first array of capillary ends are spaced apart in substantially the same manner as the wells of a microtitre tray of standard size. This allows one to simultaneously perform capillary electrophoresis on samples present in each of the wells of the tray. The system includes a stacked, dual carousel arrangement to eliminate cross-contamination resulting from reuse of the same buffer tray on consecutive executions from electrophoresis. The system also has a gel delivery module containing a gel syringe/a stepper motor or a high pressure chamber with a pump to quickly and uniformly deliver gel through the capillary tubes. The system further includes a multi-wavelength beam generator to generate a laser beam which produces a beam with a wide range of wavelengths. An off-line capillary reconditioner thoroughly cleans a capillary cartridge to enable simultaneous execution of electrophoresis with another capillary cartridge. The streamlined nature of the off-line capillary reconditioner offers the advantage of increased system throughput with a minimal increase in system cost.
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Kane Thomas E.
Kernan John R.
Li Qingbo
Liu Changsheng
Sharer Michael V.
Spectrumedix Corporation
Starsiak Jr. John S.
Warden Jill
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