Automated nucleic acid isolation

Chemistry: analytical and immunological testing – Biological cellular material tested

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436177, 436178, 422 681, 422 99, 422101, 422102, 422104, 422939, 422942, 422948, 4352851, 4352872, 4352873, 4352883, 4352885, 4353051, 4353061, 935 85, G01N 3348

Patent

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058638016

ABSTRACT:
The present invention relates to a device and a method of use for that device for the automated preparation of nucleic acid from a biological sample. The device relates to a cassette in which all chemical manipulations occur, which includes a storage/transfer strip where the prepared nucleic acid is deposited and stored without contamination. Moreover, the waste of the preparation protocol is contained in the cassette, which, upon the separation of the filled storage/transfer strip is completely sealed off from the environment. In a preferred embodiment, the inventive device can prepare nucleic acid preparations from up to 24 different biological samples at a time.

REFERENCES:
patent: 5100626 (1992-03-01), Levin
patent: 5114858 (1992-05-01), Williams et al.
patent: 5346999 (1994-09-01), Cathcart et al.
patent: 5498392 (1996-03-01), Wilding et al.
Shofi et al., Electronic and Communications in Japan, Part 2, 72(10):52-59 (1989).
Esashi et al., Sensors and Actuators, 20:163-169 (1989).

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