Automated method for treatment of samples on solid supports

Details Automated method for treatment of samples on solid supports Automated method for treatment of samples on solid supports

2007-01-02

2007-01-02

Alexander, Lyle A. (Department: 1743)

Chemistry: analytical and immunological testing

Automated chemical analysis

Utilizing a centrifuge or compartmented rotor

C436S043000, C436S049000, C436S063000, C436S177000, C422S062000, C422S064000, C422S067000, C422S068100, C422S072000

Reexamination Certificate

active

10058462

ABSTRACT:
The automated sample-on-solid-support processing system of the present invention comprises a computer-based control unit and a main unit comprising a variable-speed centrifuge having an openable vacuum-tight chamber and a centrifuge rotor with a plurality of multi-sample holding positions, a liquid solvent supply subsystem which feeds solvent to a plurality of dispensing stations in the centrifuge chamber, a temperature control subsystem, and a vacuum subsystem. A sample/collection container includes a plurality of wells, each for separating a sample from its solid support when solvent is dispensed into the wells and the centrifuge is activated at a low speed. Operation of the centrifuge at high speed concentrates the cleaved sample in collection wells. In the preferred embodiment bar code reader or other identification means, preferably a non-contact reader, can be included in the chamber to allow sample carriers to be identified.

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