Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Biological or biochemical
Reexamination Certificate
2006-02-07
2006-02-07
Martinell, James (Department: 1634)
Data processing: measuring, calibrating, or testing
Measurement system in a specific environment
Biological or biochemical
C702S020000
Reexamination Certificate
active
06996474
ABSTRACT:
The invention relate to an automated method for identifying related biomolecular sequences having defined features of interest from databases, the databases comprising at least a first and a second set of sequences, each set being derived from a different type of organism, comprising the steps of: a) establishing from the first set of sequences a non-redundant list of query sequences having the defined features of interest (first family members), using a database search program; b) performing sequence alignments with the first family members in a second set of sequences derived from a second type of organism, using a database search program and a preset similarity threshold, giving a list of second family members: c) establishing a two dimensional matrix displaying the first and second family members and their respective similarity values resulting from step (b), optionally displaying only those second family members having similarity values exceeding a preset threshold value; d) selecting from the matrix those pairs of first and second family members for which the similarity values are the best among all of the alignments that involve one of the two pair's members (orthologs).
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Colinge Jacques
Hooft Van Huijsduijnen Rob
Applied Research Systems ARS Holding N.V.
Browdy and Neimark , P.L.L.C.
Martinell James
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