Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase
Patent
1994-12-09
1997-01-28
Schain, Howard E.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving hydrolase
435 4, 435268, 435810, 435962, 435963, 436 63, 436 73, 436 74, 436 76, 514836, C12Q 134, G01N 3300
Patent
active
055977022
ABSTRACT:
Detection of lead present in a sample, comprising the steps of: (a) adding a lead recovery agent to an assay solution containing lead from the sample; (b) adding to the assay solution a disulfide enzyme which is inhibited in the presence of lead; and (c) correlating the activity of the disulfide enzyme to the amount of lead in the sample. The lead recovery agent enhances the sensitivity and accuracy of the assay such that the assay can be readily automated for detection of lead in whole blood using commercially available automation systems.
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Boltinghouse, Jr. Gary L.
Brackett John M.
Finley David M.
Ramp John M.
Shaffar Mark R.
Abbott Laboratories
Mohamed Abdel A.
Schain Howard E.
Weinstein David L.
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