Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...
Patent
1988-02-11
1991-09-17
Kepplinger, Esther L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
435805, 435 14, 436 46, 436 50, 436162, 436165, 436169, 422 56, 422 57, 422 58, 422 67, C12Q 100, G01N 2177
Patent
active
050494872
ABSTRACT:
A method for determining the presence of an analyte in a fluid is described along with various components of an apparatus specifically designed to carry out the method. The method involves taking a reflectance reading from one surface of an inert porous matrix impregnated with a reagent that will interact with the analyte to produce a light-absorbing reaction product when the fluid being analyzed is applied to another surface and migrates through the matrix to the surface being read. Reflectance measurements are made at two separate wavelengths in order to eliminate interferences, and a timing circuit is triggered by an initial decrease in reflectance by the wetting of the surface whose reflectance is being measured by the fluid which passes through the inert matrix. The method and apparatus are particularly suitable for the measurement of glucose levels in blood without requiring separation of red blood cells from serum or plasma.
REFERENCES:
patent: 3992158 (1976-11-01), Przybylowicz et al.
patent: 4059405 (1977-11-01), Sodickson et al.
patent: 4420566 (1983-12-01), Jessop et al.
patent: 4627445 (1986-12-01), Garcia et al.
patent: 4637403 (1987-01-01), Garcia et al.
patent: 4787398 (1988-11-01), Garcia et al.
Tietz (ed.), Textbook of Clinical Chemistry, (W. B. Saunders Company, Philadelphia) 1986, pp. 267-269.
Jurik Frank
McGarraugh Geoffery
Phillips Roger
Underwood Ray
Kepplinger Esther L.
Lifescan Inc.
Neeley Richard L.
Spiegel Carol A.
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