Chemistry: molecular biology and microbiology – Apparatus – Including condition or time responsive control means
Reexamination Certificate
2005-08-23
2005-08-23
Chin, Christopher L. (Department: 1641)
Chemistry: molecular biology and microbiology
Apparatus
Including condition or time responsive control means
C435S287100, C435S817000, C422S067000, C422S091000, C204S403010, C204S403140
Reexamination Certificate
active
06933143
ABSTRACT:
An electronic controller, such as a programmed microcontroller, controls a series of pumps to automatically sequence the pumping of the individual fluids required by the ELISA procedure into a cell (or cells) necessary to produce a reporter, including the addition of o-nitrophenyl beta-D galactopyranoside substrate of the enzyme (“ONP-GP”), control the positioning of the carrier of the reporter adjacent the reporter sensor, analyze the data obtained from the reporter sensor and display the concentration of the bioagent determined from the analysis of the foregoing data. Once started, the apparatus, governed by the program, conducts the test automatically in the shortest time known to date, without the necessity for human intervention.
REFERENCES:
patent: 4680258 (1987-07-01), Hammerling et al.
patent: 6562209 (2003-05-01), Sullivan et al.
John R. Crowther, “Methods in Molecular Biology,” Humana Press, (Feb. 24, 1995).
R. Colin Hughes, et al., “Neuraminidase and β-Galactosidase of D. pneumoniac,” The Extracellular Glycosidases of Diplococcus pneumoniae, vol. 3 (No. 10), pp. 1535-1543, (Oct. 24, 1964).
Edited by Paul D. Boyer, et al., “The Enzymes,” Hydrolytic Cleavage (Part A), 2nd ed., Academic Press (New York and London), pp. 409-430, (Feb. 24, 1960).
Sullivan Brian M.
Zsolnay Denes L.
Chin Christopher L.
Do Pensee T.
Goldman Ronald M.
Northrop Grumman Corporation
Thousand Connie M.
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