Chemistry: molecular biology and microbiology – Apparatus – Bioreactor
Reexamination Certificate
2011-03-15
2011-03-15
Beisner, William H (Department: 1775)
Chemistry: molecular biology and microbiology
Apparatus
Bioreactor
C435S297200, C435S303100, C435S809000, C435S287100
Reexamination Certificate
active
07906323
ABSTRACT:
The present invention provides a feedback controlled bioculture platform for use as a precision cell biology research tool and for clinical cell growth and maintenance applications. The system provides individual closed-loop flowpath cartridges, with integrated, aseptic sampling and routing to collection vials or analysis systems. The system can operate in a standard laboratory or other incubator for provision of requisite gas and thermal environment. System cartridges are modular and can be operated independently or under a unified system controlling architecture, and provide for scale-up production of cell and cell products for research and clinical applications. Multiple replicates of the flowpath cartridges allow for individual, yet replicate cell culture growth and multiples of the experiment models that can be varied according to the experiment design, or modulated to desired cell development of cell culture end-points. The integral flowpath cartridge aseptic sampling system provides for dynamic analysis of metabolic products or representative cells from the culture.
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Cannon Thomas F.
Cohn Laura K.
Kosnik Paul
Quinn Peter D.
Beisner William H
Nixon & Peabody LLP
Tissue Genesis, Inc.
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