Automated apparatus for use in peptide synthesis

Details Automated apparatus for use in peptide synthesis Automated apparatus for use in peptide synthesis

1991-12-19

1993-08-31

Housel, James C.

Chemical apparatus and process disinfecting, deodorizing, preser

Analyzer, structured indicator, or manipulative laboratory...

Sample mechanical transport means in or for automated...

422 63, 422 81, 422100, 422101, 422131, 422138, 435313, 435316, 436 43, 436 89, 935 87, 935 88, C07K 108, C12M 100

Patent

active

052406806

ABSTRACT:
An automated apparatus for use in cleaving, deprotecting and purifying synthesized polypeptides immobilized on solid phase particles. The apparatus includes cleavage and extraction vessels where peptide cleavage from solid-phase particles, and extraction of scavenger reagents occurs, respectively, and structure for automated transfer of (i) reaction solutions into and out of the cleavage vessel, (ii) peptide solution from the cleavage vessel to the extraction vessel, and (iii) extraction solvent into the extraction vessel, in dispersed form. Excess extraction solvent is removed from a side arm in the extraction vessel.

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