Autologous dermal fibroblasts for the repair of skin and soft ti

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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604 51, 623 11, 623 15, A61F 202, A61F 210, A61M 3100

Patent

active

056653727

ABSTRACT:
The application concerns a method of repairing sequelae of acne vulgaris in a subject which comprises the steps of: a) providing a fibroblast-seeded clot having dermal fibroblasts derived from the subject, said fibroblasts being substantially free of cells other than fibroblasts, and said clot being substantially free of proteins that are immunogenic in the subject; b) abrading a site of sequelae of acne vulgaris of a subject to the level of the middle or deep dermis; and c) applying the clot to the abraded site, so that the seeded fibroblasts are juxtaposed to dermis.

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