Autoinducer molecules and uses therefor

Details Autoinducer molecules and uses therefor Autoinducer molecules and uses therefor

2004-05-11

2008-10-28

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S153000

Reexamination Certificate

active

07442798

ABSTRACT:
Novel bacterial quinolone signal molecules and, more particularly,pseudomonasquinolone signal (“PQS”) molecules, e.g., 2-heptyl-3-hydroxy-4-quinolone, and analogs and derivatives thereof are described. Therapeutic compositions containing the molecules, and therapeutic methods, methods of for regulating gene expression, methods for identifying modulators of the autoinducer molecules, and methods of modulating quorum sensing signaling in bacteria using the compounds of the invention are also described.

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