Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1993-08-09
1997-01-07
Trinh, Ba Kim
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
435 4, C07D30733
Patent
active
055918727
ABSTRACT:
Autoinducer molecules, e.g., N-(3-oxododecanoyl)homoserine lactone, for Pseudomonas aeruginosa are described. The molecules regulate gene expression in the bacterium. Therapeutic compositions and therapeutic methods involving analogs and/or inhibitors of the autoinducer molecules also are described. The molecules are useful for treating or preventing infection by Pseudomonas aeruginosa.
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Eberhard Anatol
Gray Kendall M.
Greenberg Everett P.
Iglewski Barbara H.
Passador Luciano
Hanley Elizabeth A.
The University of Iowa Research Foundation
Trinh Ba Kim
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