Augmentation of wound healing by elF-4E mRNA and EGF mRNA

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

10001563

ABSTRACT:
There is provided a method of augmenting transient protein synthesis in a cell by delivering to the cell mRNA functionally related to protein production. Also provided is a method of augmenting transient protein synthesis in cells by increasing protein synthesis of growth factors from endogenous cellular mRNA and exogenous mRNA delivered to the cells. A treatment for transiently increasing protein production in cells, said treatment comprising mRNA functionally related to protein production is also provided. There is provided a method of augmenting wound healing by delivering mRNA functionally related to wound healing. Further provided is a therapeutic for transiently increasing protein synthesis in cells, said therapeutic comprising mRNA related to protein production.

REFERENCES:
Steenos, H. (Scand. Journal Plastic Reconst. Hand Surgery, 1994; vol. 28, pp. 95-105).
Andree C, Swain WF, Page CP, Macklin MD, Slama J, Hatzis D, Eriksson E. (1994) Proc Natl Acad Sci USA 91:12188-12192.
Bell GI, Gong NM, Stermien MM. (1986) Nucleic Acid Res 14(21):8427-8433.
Bennett NT, Schultz GS. (1993). Am J Surg 165;728-734.
Brown GL, Curtsinger LJ, White M, Mitchell RO, Pietsch J. (1988) Ann Surg 208(6);788-793.
Callis J, Fromm M, Walbot V. (1987) Nucleic Acids Res 15(14):5823-5831.
Cheng L, Ziegelhoffer PR, Yang N-S. (1993) Proc Natl Acad Sci USA 90:4455-4459.
De Benedetti A., Rhodes R.E. (1990) Proc. Natl. Acad. Sci USA 87:8212-8216.
Hiremath, L. S.,. Rychlik W, Joshi, S, Domier, LL, Rhoads RE. (1989) J Biol Chem 264:1132-1138 (published erratum 264:21431).
Koromilas, A.E., Lazartis-Karatzas, A., Sonenberg, N. (1992) EMBO J. 11:4153-4158 (published erratum 11:5138).
Lazaris-Karatzas, A. Montine, K.S, Sonenberg, N. (1990) Nature 345:544-547.
Qui P, Ziegelhoffer P, Sun J, Yang NS. (1996). Gene Therapy 3:262-268.
Sohn R.L., Murray M.T., Schwarz, K., Nyitray J., Purray P., Franko A.P., Palmer K., Diebel L.N., Dulcavsky S.A. (2001) Wound Rep. Reg. 9:287-296.
Yang N-S, Burkholder J, Roberts B, Martinell B, McCabe D. (1990) Proc. Natl. Acad. Sci USA 87:9568-9572.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Augmentation of wound healing by elF-4E mRNA and EGF mRNA does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Augmentation of wound healing by elF-4E mRNA and EGF mRNA, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Augmentation of wound healing by elF-4E mRNA and EGF mRNA will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3743163

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.